P-414 Trends in patient age at planned oocyte cryopreservation

Abstract Study question Did the age of women who underwent Planned Oocyte Cryopreservation (POC) change in last decade? Summary answer Mean presenting for POC decreased from 38.2±2.8 to 35.6±2.7. Proportion <36 increased 13% 2011 51% 2022. What is known already had reported literature date 37-8. Given that efficacy strongly related age, some clinicians advice considering complete procedure before 35. design, size, duration Retrospective, observational multicenter study all cycles January October Women oocyte cryopreservation other indications were excluded. Participants/materials, setting, methods In all, 4021 at least one cycle two large private IVF units belonging same medical organization Israel. The main outcome measure was first cycle. Total number each year and every woman recorded. Data analyzed using SPSS version 23. ANOVA used test whether mean differed significantly throughout years. Main results role chance Since 2011, when approved Israel, until end 2022, our units. per gradually 62 979 2021 (last with full data). declined year, 35.6±2.7 proportion aged < 36 35% 2019 further 2022 (R = 0.20, p value<0.01). Limitations, reasons caution This performed a high-socioeconomic catchment area country. may limit generalizability findings populations. addition, usage rate delivery rates these patients are not yet. Wider implications significant decrease women<36 present growing awareness infertility possibly younger women. Trial registration applicable